The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Medical Conditions Causing Mania or Mania-Like Episodes: Pathogenesis
 • Bipolar Disorder -> Combination of individual, genetic,
Conditions Causing Mania ... or Mania-Like Episodes ... #Causes #Differential ... #Diagnosis #Pathophysiology ... #Psychiatry
Feedback Loop: Prolactin (PRL)
 • PRL levels exhibit diurnal, menstrual, and age-related variation
 • TRH has
Prolactin #PRL #FeedbackLoop ... #endocrinology ... #pathophysiology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
GrowthHormone #GH #FeedbackLoop ... #endocrinology ... #pathophysiology
Benzodiazepines: Mechanism of Action and Side Effects
 • Decr spinal cord activity -> Muscle relaxant
Decr fear, Decr panic ... Benzodiazepines #Psychiatry ... #Pharmacology #pathophysiology
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
disease course Manic ... MoodDisorders #Diagnosis #Pathophysiology ... Signs #Symptoms #Psychiatry
Panic Disorder: Pathogenesis and clinical findings
Social Factors
 • Parenting and infant attachment
 • Childhood illness/abuse
 •
Panic Disorder: ... Disorder - Panic ... the event of a panic ... BehavioralDisorder #Pathophysiology ... symptoms #signs #psychiatry
Seasonal Affective Disorder: Pathogenesis and clinical findings

Symptoms (included in the DSM-V) - Two Major Depressive episodes
depression to mania ... MoodDisorders #Diagnosis #Pathophysiology ... Signs #Symptoms #Psychiatry
Social Anxiety Disorder (SAD) - Pathophysiology 
Excessive fear of one or more social situations
 • Safety
Disorder (SAD) - Pathophysiology ... Behavioral Symptoms: Panic ... BehavioralDisorder #SAD #Pathophysiology ... symptoms #signs #psychiatry