The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
Cell (Temporal) Arteritis ... palpation - Vasculitic ... GiantCell #Temporal #Arteritis ... #Pathophysiology ... Signs #Symptoms #Vasculitis
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
IgA Vasculitis – ... Arthralgia's (common), arthritis ... and ankles) #HSP ... #IgA #Vasculitis ... HenochScholeinPurpura #Pathophysiology
Menstrual Cycle Physiology: Ovarian Cycle – Brief Overview
LH and FSH are required for follicular development and
not implant #MenstrualCycle ... #OvarianCycle #pathophysiology ... #menstruation #endocrinology
Menstrual Cycle Physiology: The Hypothalamic-Pituitary-Ovarian Axis
Estrogen, when released:
 • Negatively feeds back on the hypothalamus and
#MenstrualCycle ... #pathophysiology ... HypothalamicPituitary #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Ovulation Explained

Around Day 14, estrogen exerts sudden +++ positive feedback
for clarity) #MenstrualCycle ... #OvarianCycle #pathophysiology ... #Ovulation #endocrinology
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis ... Inflammation of skin (esp ... blood vessels (vasculitis ... blood to limbs (esp ... RheumatoidArthritis #RA #pathophysiology
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Pathology of the Hip ... • Arthritis ... • Congenital hip ... Iatrogenic • Hip ... Trendelenburg #Gait #pathophysiology
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
• Posterior hip ... wall • Anterior hip ... impact onto lateral hip ... weight-bear • Arthritic ... msk #diagnosis #pathophysiology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
- Arthralgia, Arthritis ... Osteonecrosis Esp ... Complications #pathophysiology
Menstrual Cycle Physiology: Ovarian Cycle – Luteal Phase Explained
 • The LH surge can be thought
Ovarian Cycle #MenstrualCycle ... #OvarianCycle #pathophysiology ... #LutealPhase #endocrinology