The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology diagnosis complications psychiatry criteria msk ophthalmology orthopedics peds genetics gh growthhormone otitismedia pituitary 21hydroxylasedeficiency 21ohd achilles adhd alzheimersdisease anaphylaxis
Post-Traumatic Stress Disorder (PTSD) Neurochemical abnormalities • Hyper-vigilance • Emotional hyper-arousal • Exaggerated startle reflex • Anxiety
StressDisorder #PTSD #BehavioralDisorder ... Pathophysiology #diagnosis #symptoms ... #signs #psychiatry
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
Anaphylaxis: Signs ... Acute onset of skin ... in the acute phase ... Signs / Symptoms ... immunology #diagnosis #signs
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
the etiology Signs ... /Symptoms: - Pretibial ... pathophysiology #endocin #endocrinology ... #symptoms #signs
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Vasculitis -> Acute ... pathophysiology #signs ... #symptoms #diagnosis
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Signs/Symptoms: ... Hyperthyroidism #endocrinology
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
chromosome 21) Signs ... / Symptoms / Complications ... pathophysiology #geriatrics ... #diagnosis #signs ... #symptoms
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
warriors") • Acute ... pre-determined etiology Signs ... /Symptoms/Complications ... TendonRupture #diagnosis #signs ... #symptoms #pathophysiology
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings - For diagnosis, must have either 26
have either 26 symptoms ... Hyperactivity-Impulsivity or >6 symptoms ... 2 settings - Symptoms ... AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... #signs #psychiatry
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
Acute Rheumatic ... , Carditis #Acute ... pathophysiology #diagnosis #signs ... #symptoms #complications
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... #FeedbackLoop #endocrinology
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