The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis signs psychiatry peds criteria etoh genetics gh growthhormone mooddisorders pituitary riskfactors syndrome withdrawal 21hydroxylasedeficiency 21ohd adhd alcohol alcoholusedisorder alzheimersdisease
Post-Traumatic Stress Disorder (PTSD) Neurochemical abnormalities • Hyper-vigilance • Emotional hyper-arousal • Exaggerated startle reflex • Anxiety
startle reflex • Anxiety ... StressDisorder #PTSD #BehavioralDisorder ... #Pathophysiology ... #diagnosis #symptoms
Panic Disorder: Pathogenesis and clinical findings Social Factors • Parenting and infant attachment • Childhood illness/abuse •
carrying anti-anxiety ... Anticipatory Anxiety ... PanicDisorder #Anxiety ... #BehavioralDisorder ... #Pathophysiology
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
etiology Signs/Symptoms ... GravesDisease #pathophysiology ... #endocin #endocrinology ... #symptoms #signs
Social Anxiety Disorder (SAD) - Pathophysiology Excessive fear of one or more social situations • Safety
Social Anxiety Disorder ... (SAD) - Pathophysiology ... of Anxiety: Mind ... SocialAnxiety #BehavioralDisorder ... #SAD #Pathophysiology
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings Symptoms (included in DSM 5 criteria) - Present during
Clinical Findings Symptoms ... suicide Other Symptoms ... partum onset) - Anxiety ... MoodDisorders #Diagnosis #Pathophysiology ... #Signs #Symptoms
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Signs/Symptoms: ... Hyperthyroidism #endocrinology ... #pathophysiology
Alcohol Use Disorder: Pathogenesis and Clinical Findings • Tolerance (reduced sensitivity to effects of EtOH) •
• Withdrawal symptoms ... , seizure, and anxiety ... AlcoholUseDisorder #EtOH #Pathophysiology ... Diagnosis #Signs #Symptoms
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings - For diagnosis, must have either 26
have either 26 symptoms ... 2 settings - Symptoms ... AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... #Pathophysiology ... #diagnosis #symptoms
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... diagnosis #signs #symptoms ... #endocrinology ... #pathophysiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... #FeedbackLoop #endocrinology ... #pathophysiology
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