The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology symptoms diagnosis orthopedics syndrome ankylosingspondylitis bulimianervosa caudaequina chronic erythematosus femoralhead fractures genetics hypertensive lupus musculoskeletal ophthalmology pagetsdisease pediatrics peds
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
Achilles Tendon ... pre-determined etiology Signs ... /Symptoms/Complications ... TendonRupture #diagnosis #signs ... pathophysiology #msk
Ankylosing Spondylitis: Pathogenesis and Clinical findings • Pain in lumbar area and gluteal region: (Dull, insidious
prominently in Achilles ... column) • Late complication ... pathophysiology #diagnosis #signs
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Erythematosus #SLE #MSK ... Musculoskeletal #Complications ... pathophysiology #signs
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... /Symptoms/Complications ... FemoralHead #Fractures #msk ... pathophysiology #signs
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
lumbar spine Signs ... / Symptoms / Complications ... CaudaEquina #Syndrome #MSK ... diagnosis #symptoms #signs
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome Signs ... /Symptoms/Complications ... fractures • Short
Upper Urinary Tract infection (UUTI): Pathogenesis and Clinical Findings Predisposing Factors: - Immunocompromised, Diabetes, - Elderly, Female
Elderly, Female (short ... lower tract: As a complication ... Pathophysiology #Signs
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
-> Cotton-wool Spots ... -> Elschnig's Spots ... ophthalmology #diagnosis #signs ... #symptoms #complications
Bulimia Nervosa: Signs and Symptoms Associated Psychological / Behavioural Features • Feelings of shame, guilt and embarrassment
Bulimia Nervosa: Signs ... Symptoms related to complications ... weight Russell's Sign ... • Sores, scars ... pathophysiology #diagnosis #signs
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... bone formation MSK ... pathophysiology #diagnosis #signs ... #symptoms #complications
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