The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Obsessive-Compulsive Disorder (OCD): Pathogenesis and clinical findings

Psychological Hypothesis
 • Cognitive behavioral model: Emotional disturbance arising from
Hypotheses • Serotonin ... of postsynaptic serotonin ... Dysregulation of anxiety ... PersonalityDisorder #Diagnosis ... #Psychiatry #Signs
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Selective Serotonin ... Side Effects • Serotonin ... sensations) #SSRIs #Serotonin ... #SideEffects #Psychiatry ... #Diagnosis #Signs
Schizotypal Personality Disorder (SPD): Pathogenesis and clinical findings
Cognitive-Perceptual
 • Magical thinking - Belief in paranormal or
Mnemonic: ME PECULIAR ... reference - Anxiety ... PersonalityDisorder #Diagnosis ... #Psychiatry #Criteria ... #Signs #Symptoms
Pathogenesis of Anxiety Disorders

Anxiety Disorders: A maladaptive emotional state causing fear,
worry, and excessive stress, characterized by:
Pathogenesis of Anxiety ... Disorders Anxiety ... norepinephrine, serotonin ... Pathophysiology #diagnosis ... #psychiatry
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Serotonin-Norepinephrine ... Nausea, Vomiting Serotonin ... #SideEffects #Psychiatry ... #Diagnosis #Signs
Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
startle reflex • Anxiety ... Pathophysiology #diagnosis ... #symptoms #signs ... #psychiatry
Antisocial Personality Disorder (ASPD): Pathogenesis and Clinical Findings
Work & lnterpersonal:
 • Home Life Troubles - Conflict
Mnemonic: CORRUPT ... PersonalityDisorder #Diagnosis ... #Psychiatry #Criteria ... #Signs #Symptoms ... #Mnemonic #CORRUPT
Borderline Personality Disorder: Pathogenesis and Clinical Findings
Behavioral Traits:
 • Unstable Relationships - Alternating extremes of idealization
/ irritability/anxiety ... PersonalityDisorder #Diagnosis ... #Psychiatry #Criteria ... #Signs #Symptoms ... #Mnemonic #AMSUICIDE
Avoidant Personality Disorder (AVPD): Pathogenesis and Clinical Findings
 • Restraint - Shows excessive restraint in intimate
Mnemonic: CRINGES ... PersonalityDisorder #Diagnosis ... #Psychiatry #Criteria ... #Signs #Symptoms ... #Mnemonic #CRINGES
Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
, seizure, and anxiety ... Pathophysiology #Diagnosis ... #Signs #Symptoms ... #Psychiatry