The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... with keratotic scaling ... pathophysiology #diagnosis ... #signs #symptoms
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
• Avulsion or shearing ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... #Systemic #Lupus ... Erythematosus #SLE #MSK ... pathophysiology #signs ... #symptoms #diagnosis
Radiculopathy: Signs and Symptoms
 • Back/Neck Pain
 • Decr Range of motion
 • Abnormal posturing
 •
Radiculopathy: Signs ... : -> Shooting, stabbing ... pain Lasegue's sign ... Radiculopathy #MSK ... #diagnosis #signs
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
ligament substance leading ... ligament substance leading ... LowAnkleSprain #Sports #MSK ... #orthopedics #Grading ... #Grades #Diagnosis
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
post-inflammatory healing ... pathophysiology #diagnosis ... #symptoms #signs ... #stages #staging ... #msk
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
pre-determined etiology Signs ... TendonRupture #diagnosis ... #signs #symptoms ... pathophysiology #msk ... #orthopedics
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
sensory • Before diagnosis ... , Stabbing) - ... MeralgiaParesthetica #MSK ... #differential #diagnosis ... #signs #symptoms
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
#Dislocation #Diagnosis ... #signs #symptoms ... #msk #orthopedics
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
lumbar spine Signs ... pain (shooting, stabbing ... CaudaEquina #Syndrome #MSK ... pathophysiology #diagnosis ... #symptoms #signs