The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology signs complications orthopedics syndrome vasculitis fractures temporal allergy definitions disease giantcell hypersensitivity injury psoriaticarthritis ra reactions rheumatoidarthritis shoulder types
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... Ex: Antibiotic allergies ... Erythematosus, Reactive Arthritis ... #Types #Classification ... #Diagnosis #Definitions
Giant Cell (Temporal) Arteritis: Clinical findings and Complications Signs/Symptoms: - Headache (usually constant, superimposed by waves
Cell (Temporal) Arteritis ... Complications Signs/Symptoms ... Stroke or TIA-like symptoms ... GiantCell #Temporal #Arteritis ... #diagnosis #Vasculitis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
- Arthralgia, Arthritis ... Erythematosus #SLE #MSK ... pathophysiology #signs #symptoms ... #diagnosis
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
Anaphylaxis: Signs and Symptoms ... exposure to a likely allergen ... exposure to known allergen ... Signs / Symptoms ... pathophysiology #immunology #diagnosis
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
Cell (Temporal) Arteritis ... old; F>M Signs/Symptoms ... GiantCell #Temporal #Arteritis ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
lateral hip Signs/Symptoms ... weight-bear • Arthritic ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology ... #signs #symptoms
Meralgia paresthetica: Pathogenesis and Clinical Findings Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica •
paresthetica • Symptoms ... 3-6 months of symptom ... sensory • Before diagnosis ... MeralgiaParesthetica #MSK ... #differential #diagnosis
Open Fractures: Mechanisms, Clinical Features and Complications Gustilo-Anderson Classification: • Type I - Wound <
Gustilo-Anderson Classification ... GustiloAnderson #Classification ... Open #Fractures #Diagnosis ... Complications #MSK
Myelopathy - Injury to the entire spinal cord - Signs and Symptoms • Ataxia (early sign)
cord - Signs and Symptoms ... #Myelopathy #diagnosis ... #signs #symptoms ... #msk
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
leading to an allergic ... leading to an allergic ... An allergic reaction ... #Types #Classification ... #Diagnosis #Definitions
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