The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
Major Depressive ... MajorDepressiveDisorder #Depression ... MoodDisorders #Diagnosis ... #Pathophysiology ... Signs #Symptoms #Psychiatry
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
of Pelvic Ring Fractures ... #PelvicRing #Fractures ... #Orthopedics #MSK ... #diagnosis #complications ... #pathophysiology
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
Subtrochanteric Femur Fracture ... low energy fall fractures ... #msk #orthopedics ... #diagnosis #differential ... #causes #pathophysiology
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... • Non-union of fracture ... #FemoralHead #Fractures ... #msk #diagnosis ... #pathophysiology
Lewy Body Dementia: Pathogenesis and Clinical Findings
Lewy Body Dementia is a sub-category of major or mild
a hierarchy of diagnostic ... (required for diagnosis ... delusions • Depression ... LewyBody #Dementia #pathophysiology ... #geriatrics #diagnosis
Spondylolysis & Spondylolisthesis: Pathogenesis and Clinical Findings

Pars interarticularis stress fracture (spondylolysis) - most frequently in the
interarticularis stress fracture ... Spondylolisthesis #MSK ... #diagnosis #pathophysiology
Bulimia Nervosa: Signs and Symptoms
Associated Psychological / Behavioural Features
 • Feelings of shame, guilt and embarrassment
/ Behavioural Features ... inducing vomiting #BulimiaNervosa ... #pathophysiology ... #diagnosis #signs ... #symptoms #psychiatry
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
maintain this state Depressive ... MoodDisorders #Diagnosis ... #Pathophysiology ... Signs #Symptoms #Psychiatry
Schizophrenia: Pathogenesis and Symptoms
Increased dopaminergic transmission in mesolimbic projection
-> Dopaminergic neurons here project into the limbic
Diminished emotional expression ... Schizophrenia #pathophysiology ... #diagnosis #symptoms ... #signs #psychiatry
Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
& Decr surface expression ... #Xeropthalmia #pathophysiology ... #ophthalmology ... #diagnosis #signs