The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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DSM 5: Elimination of the “5 Axes” Model
 • Axis I - Primary mental health disorder
mental health disorder ... - Personality disorders ... developmental disorders ... Genetic loading, ... #psychiatry #model
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
Clinical Findings Grading ... ligament substance leading ... LowAnkleSprain #Sports #MSK ... #orthopedics #Grading ... #Grades #Diagnosis
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
Bipolar Disorder ... distractibility - racing ... behaviours #Bipolar #Disorder ... MoodDisorders #Diagnosis ... Signs #Symptoms #Psychiatry
Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
Alcohol Use Disorder ... - Alcohol craving ... Pathophysiology #Diagnosis ... Signs #Symptoms #Psychiatry
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
Classification #Grades #Grading ... #Orthopedics #MSK ... #diagnosis #complications
Panic Disorder: Pathogenesis and clinical findings
Social Factors
 • Parenting and infant attachment
 • Childhood illness/abuse
 •
Panic Disorder: ... hypothalamic-pituitary-adrenal (HPA) axis ... heritability >> Panic Disorder ... Pathophysiology #diagnosis ... symptoms #signs #psychiatry
Social Anxiety Disorder (SAD) - Pathophysiology 
Excessive fear of one or more social situations
 • Safety
Social Anxiety Disorder ... Nervous System & HPA axis ... Pathophysiology #diagnosis ... symptoms #signs #psychiatry
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Metabolic / Endocrine disorders ... Healing #Stages #Orthopedics ... #msk #Staging # ... pathophysiology #diagnosis