The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... tumour causing injury ... weakness and #Acute ... #SpinalCord #Injury ... signs #symptoms #msk
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
metabolites induce injury ... within GI and URT causes ... Maternal viremia causes ... Hematogenous spread causes ... evasion techniques cause
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Acute Rheumatic ... cells -> Tissue injury ... Pancarditis and valvular injury ... , Carditis #Acute
Myelopathy - Injury to the entire spinal cord - Signs and Symptoms
 • Ataxia (early sign)
Myelopathy - Injury ... signs #symptoms #msk
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
most commonly injured ... the CFL is also injured ... (uncommonly injured ... PTFL is rarely injured ... LowAnkleSprain #Sports #MSK
Open Fractures: Mechanisms, Clinical Features and Complications
Gustilo-Anderson Classification:
 • Type I
   - Wound <
Typically "inside out" injury ... Complications #MSK
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Avulsion or shearing injury ... FemoralHead #Fractures #msk
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
possible vascular injury ... - Type 1 or 2 injury ... #Orthopedics #MSK
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
vasoconstrictive • Acute ... hyalinization causes ... BRB breakdown causes ... disc arterioles causes ... disc arterioles causes