The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis orthopedics signs symptoms fractures grades immunology sports achilles acl anaphylaxis anteriorcruciateligament classification closedangle discherniations femoralhead glaucoma hypersensitivityreaction lowanklesprain neurology
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
degranulation, leading ... to an allergic ... cells recruited Complications ... : • Acute Asthma ... #Immunology #pathophysiology
Low Ankle Sprain: Pathomechanics and Clinical Findings Grading Ligament Sprains l: Minimal ligament disruption, mild swelling & tenderness,
Clinical Findings Grading ... (uncommonly injured ... LowAnkleSprain #Sports #MSK ... #orthopedics #Grading ... Grades #Diagnosis #pathophysiology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... spinal artery injury ... weakness and #Acute ... Syndromes #diagnosis #pathophysiology ... signs #symptoms #msk
Disc Herniations - Pathogenesis and Complications • 90% of Lumbar disc herniations happen at L4/5 and L5/S1 •
Pathogenesis and Complications ... -> Mechanical loading ... DiscHerniations #complications ... #msk #pathophysiology
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
Acute Rheumatic ... cells -> Tissue injury ... , Carditis #Acute ... RheumaticFever #pathophysiology ... signs #symptoms #complications
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
possible vascular injury ... - Type 1 or 2 injury ... Classification #Grades #Grading ... #Orthopedics #MSK ... #pathophysiology
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
Acute onset of skin ... exposure to known allergen ... symptoms in the acute ... Signs / Symptoms / Complications ... #Anaphylaxis #pathophysiology
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Avulsion or shearing injury ... Signs/Symptoms/Complications ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
warriors") • Acute ... Signs/Symptoms/Complications ... signs #symptoms #pathophysiology ... #msk #orthopedics
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle ... Increased pressure gradient ... Signs / Symptoms / Complications ... Photophobia #Acute ... ClosedAngle #Glaucoma #pathophysiology
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