The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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symptoms msk psychiatry complications anorexianervosa bulimianervosa causes pagetsdisease stages staging syndrome achilles acquired acute adhesivecapsulitis ankylosingspondylitis anterior bonestrength classification depression
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
Stress Fracture: ... => Microscopic fractures ... StressFractures #msk #orthopedics ... #pathophysiology ... #symptoms #signs
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings • Subtrochanteric region spans 5 cm distally from the
Subtrochanteric Femur Fracture ... young people) • Osteoporosis ... #msk #orthopedics ... #diagnosis #differential ... #causes #pathophysiology
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... #msk #diagnosis ... #pathophysiology ... #signs #symptoms ... #orthopedics
Osteoporosis: Pathogenesis and risk factors • Age > 30 (post-peak bone mass) • Post-menopausal women ->
Osteoporosis: Pathogenesis ... Hyperthyroid #Osteoporosis ... #pathophysiology ... #signs #symptoms ... #diagnosis
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
bilateral rami fractures ... Grade 2 - Rami fracture ... Grades #Grading #Orthopedics ... #MSK #diagnosis ... complications #pathophysiology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome Signs ... mineral density and osteoporosis ... Incr Skeletal fractures ... Syndrome #genetics #pathophysiology
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
Glucocorticoid-Induced Osteoporosis ... Glucocorticoids #steroids #Osteoporosis ... #pathophysiology ... #signs #symptoms ... #diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Normal CK • Osteoporosis ... Complications #pathophysiology ... #signs #symptoms ... #diagnosis
Spondylolysis & Spondylolisthesis: Pathogenesis and Clinical Findings Pars interarticularis stress fracture (spondylolysis) - most frequently in the
interarticularis stress fracture ... XR — scotty dog sign ... Spondylolisthesis #MSK #diagnosis ... #pathophysiology ... #signs #symptoms
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
(and disruptors ... disrupts local ... #Stages #Orthopedics ... #msk #Staging #pathophysiology ... #diagnosis #disruptors
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