The Calgary Guide to Understanding Disease @TheCalgaryGuide
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signs symptoms complications msk orthopedics anaphylaxis gh growthhormone ophthalmology otitismedia pituitary urology achilles agammaglobulinemia allergy ankylosingspondylitis anterior avascularnecrosis benign bph
Feedback Loop: Prolactin (PRL) • PRL levels exhibit diurnal, menstrual, and age-related variation • TRH has
Prolactin #PRL #FeedbackLoop ... #endocrinology ... #pathophysiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
GrowthHormone #GH #FeedbackLoop ... #endocrinology ... #pathophysiology
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
Acute onset of skin ... symptoms in the acute ... #Anaphylaxis #pathophysiology ... #immunology #diagnosis
Anaphylaxis: Treatments (Acute) Additional Info: • IV steroids may be considered for prevention of late phase reactions.
Anaphylaxis: Treatments (Acute ... Treatments #Management #pathophysiology ... #immunology
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
GravesDisease #pathophysiology ... #endocin #endocrinology ... symptoms #signs #diagnosis
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... Overproduction #diagnosis ... signs #symptoms #endocrinology ... #pathophysiology
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
Complications: • Acute ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Vasculitis -> Acute ... Complications #pathophysiology ... signs #symptoms #diagnosis
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
Acute Rheumatic ... , Carditis #Acute ... RheumaticFever #pathophysiology ... #diagnosis #signs
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings The epidemiology of this disease is 1/340,000 births and roughly double
40% of patients diagnosed ... Agammaglobulinemia #XLinked #pathophysiology ... #immunology
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