The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis symptoms complications staging adhesivecapsulitis bipolar classification depression disorder disruptors femoralhead fracture frozenshoulder grades healing majordepressivedisorder mdd pagetsdisease pelvicring serotonin
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
subthreshold mechanical loading ... from continued loading ... StressFractures #msk ... #orthopedics #pathophysiology ... #symptoms #signs
Bipolar Disorder: Pathogenesis and Clinical Findings • Disruption of emotional homeostasis • Oscillation between mood states
distractibility - racing ... Bipolar #Disorder #MoodDisorders ... #Diagnosis #Pathophysiology ... #Signs #Symptoms ... #Psychiatry
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
Grade 2 - Rami fracture ... posterior ilium fracture ... Classification #Grades #Grading ... #Orthopedics #MSK ... complications #pathophysiology
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... #msk #diagnosis ... #pathophysiology ... #signs #symptoms ... #orthopedics
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings Symptoms (included in DSM 5 criteria) - Present during
with psychotic features ... MajorDepressiveDisorder #Depression #MoodDisorders ... #Diagnosis #Pathophysiology ... #Signs #Symptoms ... #Psychiatry
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
, humeral head fracture ... FrozenShoulder #pathophysiology ... diagnosis #symptoms #signs ... #stages #staging ... #msk
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Inflammatory Stage ... site Soft Callus Stage ... #Stages #Orthopedics ... #msk #Staging # ... pathophysiology
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
bone formation MSK ... -> Pathologic fractures ... Nephrolithiasis (Kidney Stones ... PagetsDisease #pathophysiology ... #diagnosis #signs
Serotonin Syndrome: Pathogenesis and Clinical Findings Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
combination of mental status ... Altered Mental Status ... Serotonin #Syndrome #Pathophysiology ... #Psychiatry #Diagnosis ... #Signs #Symptoms
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