The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
Major Depressive Disorder ... Seasonal Affective Disorder ... MajorDepressiveDisorder #Depression #MoodDisorders ... #Diagnosis #Pathophysiology ... Signs #Symptoms #Psychiatry
Seasonal Affective Disorder: Pathogenesis and clinical findings

Symptoms (included in the DSM-V) - Two Major Depressive episodes
Seasonal Affective Disorder ... SAD #Seasonal #AffectiveDisorder ... #MoodDisorders ... #Diagnosis #Pathophysiology ... Signs #Symptoms #Psychiatry
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
Bipolar Disorder ... behaviours #Bipolar #Disorder ... #MoodDisorders ... #Diagnosis #Pathophysiology ... Signs #Symptoms #Psychiatry
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Stevens-Johnson Syndrome ... relapse of bipolar disorder ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Fecal Incontinence - Pathogenesis and Complications
Continence mechanisms are impaired
 • Local neuronal damage
 • External and
ignored • Movement Disorders ... irritable bowel syndrome ... #Incontinence #geriatrics ... #pathophysiology
Oppositional Defiant Disorder (ODD): Pathogenesis and clinical findings
 - Must have >4 symptoms for >6 months,
Oppositional Defiant Disorder ... progress to conduct disorder ... mood and anxiety disorders ... BehavioralDisorder #Pathophysiology ... symptoms #signs #psychiatry