The Calgary Guide to Understanding Disease @TheCalgaryGuide
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First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
Anti-Psychotics: Mechanisms ... AntiPsychotics #FirstGeneration ... #Mechanisms #SideEffects ... #pharmacology #
Second Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) - Examples: Clozapine, Olanzapine, Quetiapine, Risperidone, Zotepine, Paliperidone,
Antipsychotics: Mechanisms ... Cardio-metabolic effects - Mechanism ... SecondGeneration #Mechanisms ... #SideEffects #pharmacology
Open Fractures: Mechanisms, Clinical Features and Complications
Gustilo-Anderson Classification:
 • Type I
   - Wound <
Open Fractures: Mechanisms ... Clinical Features and Complications ... Fractures #Diagnosis #Complications
Fecal Incontinence - Pathogenesis and Complications
Continence mechanisms are impaired
 • Local neuronal damage
 • External and
Pathogenesis and Complications ... Continence mechanisms ... impairment Continence mechanisms
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Mood Stabilizers: Mechanism ... MoodStabilizers #Mechanism ... Pathophysiology #Psychiatry #Pharmacology
Benzodiazepines: Mechanism of Action and Side Effects
 • Decr spinal cord activity -> Muscle relaxant
Benzodiazepines: Mechanism ... Benzodiazepines #Psychiatry #Pharmacology
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Reuptake Inhibitors: Mechanisms ... Pathophysiology #Pharmacology
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Inhibitors(SNRIs): Mechanisms ... Pathophysiology #Pharmacology
Third Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) Example: Aripiprazole
Dopamine D2 Receptor Partial Agonist
 • Binds
Antipsychotics: Mechanisms ... ThirdGeneration #Mechanisms ... #SideEffects #pharmacology
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
Ring Fractures: Mechanisms ... Clinical Features and Complications ... MSK #diagnosis #complications