The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis symptoms msk psychiatry vasculitis endocrinology lupus ophthalmology sideeffects sle erythematosus genetics giantcell inhibitors pediatrics peds pharmacology serotonin systemic withdrawal
Giant Cell (Temporal) Arteritis: Clinical findings and Complications Signs/Symptoms: - Headache (usually constant, superimposed by waves
) Arteritis: Clinical ... findings and Complications ... Signs/Symptoms ... #Arteritis #Complications ... #Signs #Symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
- Arthralgia, Arthritis ... Myopathy (Also caused ... Musculoskeletal #Complications ... #pathophysiology ... #signs #symptoms
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
Giant Cell (Temporal ... ) Arteritis: Pathogenesis ... yrs old; F>M Signs ... #Arteritis #Pathophysiology ... #Diagnosis #Signs
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... /Symptoms/Complications ... weight-bear • Arthritic ... msk #diagnosis #pathophysiology ... #signs #symptoms
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
- Budd Chiari Syndrome ... Gastrointestinal #Complications ... #pathophysiology ... #signs #symptoms
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... / Symptoms / Complications ... AlzheimersDisease #Dementia #pathophysiology ... geriatrics #diagnosis #signs
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... lumbar spine Signs ... / Symptoms / Complications ... #MSK #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... • Other rare causes ... visual acuity • Bitemporal ... Carpal Tunnel Syndrome ... Overproduction #diagnosis #signs
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... Signs/Symptoms ... /Complications: ... #genetics #pathophysiology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
Primary Sjogren’s Syndrome ... like rheumatoid arthritis ... erythematosus (SLE) Signs ... #Pathophysiology ... #Diagnosis #Signs
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