The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis symptoms pathophysiology complications sle temporal erythematosus giantcell systemic allergic allergy classification cranialarteritis criteria definitions disease extraarticular gastrointestinal giantcellarteritis henochscholeinpurpura
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... - Budd Chiari Syndrome ... #Systemic #Lupus ... pathophysiology #signs
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
Cell (Temporal) Arteritis ... yrs old; F>M Signs ... palpation - Vasculitic ... GiantCell #Temporal #Arteritis ... #Symptoms #Vasculitis
Giant Cell (Temporal) Arteritis: Clinical findings and Complications Signs/Symptoms: - Headache (usually constant, superimposed by waves
Cell (Temporal) Arteritis ... Complications Signs ... GiantCell #Temporal #Arteritis ... Complications #Signs ... Symptoms #diagnosis #Vasculitis
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
Primary Sjogren’s Syndrome ... like rheumatoid arthritis ... RA) or systemic lupus ... erythematosus (SLE) Signs ... Pathophysiology #Diagnosis #Signs
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... - Arthralgia, Arthritis ... #Systemic #Lupus ... pathophysiology #signs
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
IgA Vasculitis – ... nephrotic/nephritic syndrome ... Arthralgia's (common), arthritis ... #HSP #IgA #Vasculitis ... Pathophysiology #Diagnosis #Signs
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... Livedo Reticularis, Vasculitis ... Phenomenon #Lupus ... pathophysiology #diagnosis #signs
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
• Ex: Systemic Lupus ... Erythematosus, Reactive Arthritis ... Stevens-Johnson Syndrome
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis ... blood vessels (vasculitis ... pathophysiology #signs
Giant Cell Arteritis (Polymyalgia Rheumatica and Cranial Arteritis): Pathogenesis and Clinical Findings - Morning Stiffness (>1
Giant Cell Arteritis ... Rheumatica and Cranial Arteritis ... Pathophysiology #Signs ... Symptoms #Diagnosis #Vasculitis
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