The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Gastrointestinal Manifestations ... the pancreas, Vasculitis ... -> Acute Pancreatitis ... Gastrointestinal #Complications ... pathophysiology #signs
Giant Cell (Temporal) Arteritis: Clinical findings and Complications
Signs/Symptoms: 
 - Headache (usually constant, superimposed by waves
Cell (Temporal) Arteritis ... Signs/Symptoms ... #Complications ... #Signs #Symptoms ... #diagnosis #Vasculitis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Musculoskeletal Manifestations ... - Arthralgia, Arthritis ... Musculoskeletal #Complications ... pathophysiology #signs
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Mucocutaneous Manifestations ... Livedo Reticularis, Vasculitis ... Mucocutaneous #Manifestations ... pathophysiology #diagnosis #signs ... #symptoms #complications
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis ... Extra-articular manifestations ... blood vessels (vasculitis ... pathophysiology #signs
Kawasaki Disease: Clinical Findings
Diagnostic Criteria - Fever and 4/5 of the following:
 • Conjunctivitis
 • Polymorphous
hands & feet Signs ... /Symptoms/Complications ... : - Coronary Arteritis ... Pathophysiology #Signs ... #Symptoms #Vasculitis
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
Rheumatoid arthritis ... Extra-articular manifestations ... • Non-specific Acute-phase ... Extra-articular signs ... pathophysiology #signs
Takayasu’s Arteritis: Pathogenesis and clinical findings

 - Fatigue, weight loss, low grade fever, arthralgias
 - Incr
Takayasu’s Arteritis ... , Incr risk of Acute ... #Takayasus #Arteritis ... #Vasculitis #Diagnosis ... #Signs #Symptoms
Ankylosing Spondylitis: Extra-articular Manifestations
 • Ocular - Inflammation of the iris, the anterior part of the
Extra-articular Manifestations ... - Inflammation acute ... Extraarticular #Manifestations ... #Complications ... pathophysiology #diagnosis #signs