The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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symptoms diagnosis sle erythematosus msk pediatrics peds psychiatry syndrome 21hydroxylasedeficiency 21ohd achilles anorexianervosa anxiety arteritis behavioraldisorder criteria disease endocrinology femoralhead
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... Gastrointestinal #Complications ... #pathophysiology ... #signs #symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... #Lupus #Erythematosus ... Musculoskeletal #Complications ... #pathophysiology ... #signs #symptoms
Systemic Lupus Erythematosus (SLE): Pathogenesis • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
Systemic Lupus Erythematosus ... Pathogenesis • Genetic ... Interaction btw genetic ... #Lupus #Erythematosus ... #SLE #Pathophysiology
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
not proven) - Genetic ... yrs old; F>M Signs ... Temporal #Arteritis #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Livedo Reticularis, Vasculitis ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
(PBC), or with systemic ... lupus erythematosus ... (SLE) Signs / ... Sjogrens #Syndrome #Pathophysiology ... #Diagnosis #Signs
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome Signs ... /Symptoms/Complications ... PraderWilli #Syndrome #genetics ... #pathophysiology
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... /Symptoms/Complications ... msk #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
pre-determined etiology Signs ... /Symptoms/Complications ... TendonRupture #diagnosis #signs ... #symptoms #pathophysiology ... #msk #orthopedics
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
IgA Vasculitis – ... predisposition - Various genetic ... #HSP #IgA #Vasculitis ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs
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