The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology symptoms ankylosingspondylitis ra rheumatoidarthritis bulimianervosa criteria femoralhead genetics kawasaki manifestations msk orthopedics pagetsdisease pediatrics psoriaticarthritis psychiatry syndrome vasculitis
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome Signs ... /Symptoms/Complications ... Incr Skeletal fractures ... pulmonale #PraderWilli ... pathophysiology #peds
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... /Symptoms/Complications ... weight-bear • Arthritic ... #msk #diagnosis ... pathophysiology #signs
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis ... interstitial lung disease ... pathophysiology #signs ... #symptoms #diagnosis ... #ExtraArticular
Ankylosing Spondylitis: Pathogenesis and Clinical findings • Pain in lumbar area and gluteal region: (Dull, insidious
more constant as disease ... column) • Late complication ... bamboo spine) -> Fracture ... pathophysiology #diagnosis ... #signs #symptoms
Kawasaki Disease: Clinical Findings Diagnostic Criteria - Fever and 4/5 of the following: • Conjunctivitis • Polymorphous
Kawasaki Disease ... Clinical Findings Diagnostic ... hands & feet Signs ... /Symptoms/Complications ... : - Coronary Arteritis
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Rheumatoid arthritis ... Pathogenesis and Joint diseases ... features • RA ... Extra-articular signs ... #symptoms #diagnosis
Psoriatic Arthritis: Complications • Ocular - Inflammation of middle layer of the eye (the uvea, which
Psoriatic Arthritis ... : Complications ... Cardiac - Valvular disease ... pathophysiology #diagnosis ... #signs #symptoms
Bulimia Nervosa: Signs and Symptoms Associated Psychological / Behavioural Features • Feelings of shame, guilt and embarrassment
Bulimia Nervosa: Signs ... erosion and gum disease ... Symptoms related to complications ... pathophysiology #diagnosis ... #signs #symptoms
Ankylosing Spondylitis: Extra-articular Manifestations • Ocular - Inflammation of the iris, the anterior part of the
Inflammatory Bowel Disease ... AnkylosingSpondylitis #Extraarticular ... Manifestations #Complications ... pathophysiology #diagnosis ... #signs #symptoms
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: ... Complications ... -> Pathologic fractures ... pathophysiology #diagnosis ... #signs #symptoms
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