The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis pathophysiology lupus pediatrics sle temporal erythematosus genetics giantcell manifestations msk systemic 21hydroxylasedeficiency 21ohd ankylosingspondylitis cranialarteritis criteria disease endocrinology femoralhead
Giant Cell (Temporal) Arteritis: Clinical findings and Complications Signs/Symptoms: - Headache (usually constant, superimposed by waves
Cell (Temporal) Arteritis ... Signs/Symptoms ... #Complications ... #Signs #Symptoms ... #diagnosis #Vasculitis
Kawasaki Disease: Clinical Findings Diagnostic Criteria - Fever and 4/5 of the following: • Conjunctivitis • Polymorphous
Kawasaki Disease ... hands & feet Signs ... /Symptoms/Complications ... : - Coronary Arteritis ... #Symptoms #Vasculitis
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
Cell (Temporal) Arteritis ... yrs old; F>M Signs ... /Symptoms: - Fever ... palpation - Vasculitic ... #Symptoms #Vasculitis
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
the pancreas, Vasculitis ... Gastrointestinal #Complications ... pathophysiology #signs ... #symptoms #diagnosis
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis ... blood vessels (vasculitis ... pathophysiology #signs ... #symptoms #diagnosis ... #ExtraArticular
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
- Arthralgia, Arthritis ... Musculoskeletal #Complications ... pathophysiology #signs ... #symptoms #diagnosis
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... /Symptoms/Complications ... weight-bear • Arthritic ... pathophysiology #signs ... #symptoms #orthopedics
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome Signs ... /Symptoms/Complications ... pathophysiology #peds
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
IgA Vasculitis – ... Arthralgia's (common), arthritis ... #HSP #IgA #Vasculitis ... Pathophysiology #Diagnosis #Signs ... #Symptoms
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis #signs ... #symptoms #complications
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