The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis complications sle erythematosus extraarticular msk ra rheumatoidarthritis systemic adhesivecapsulitis ankylosingspondylitis avascularnecrosis bipolar cranialarteritis dermatomyositis disorder dm endocrinology frozenshoulder gastrointestinal
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... Gastrointestinal Manifestations ... the pancreas, Vasculitis ... Complications #pathophysiology ... #signs #symptoms
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... RA) or systemic lupus ... / Symptoms: - ... Sjogrens #Syndrome #Pathophysiology ... #Symptoms
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Manifestations ... Livedo Reticularis, Vasculitis ... #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Musculoskeletal Manifestations ... #Systemic #Lupus ... Complications #pathophysiology ... #signs #symptoms
Osteoporosis: Pathogenesis and risk factors • Age > 30 (post-peak bone mass) • Post-menopausal women ->
Leukemia) • GI diseases ... liver or kidney disease ... Corticosteroid use • Primary ... #Osteoporosis #pathophysiology ... #signs #symptoms
Kawasaki Disease: Clinical Findings Diagnostic Criteria - Fever and 4/5 of the following: • Conjunctivitis • Polymorphous
Kawasaki Disease ... hands & feet Signs ... #Pathophysiology ... #Signs #Symptoms ... #Vasculitis
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Primary Hyperthyroidism ... rare, gestational diseases ... Signs/Symptoms: ... Pretibial myxedema #Primary ... endocrinology #pathophysiology
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
swelling - GI Manifestations ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Extra-articular manifestations ... blood vessels (vasculitis ... interstitial lung disease ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Giant Cell Arteritis (Polymyalgia Rheumatica and Cranial Arteritis): Pathogenesis and Clinical Findings - Morning Stiffness (>1
Muscle Aching (Primarily ... Anemia of Chronic Disease ... CranialArteritis #Pathophysiology ... #Signs #Symptoms ... #Diagnosis #Vasculitis
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