The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology signs diagnosis lupus peds erythematosus genetics geriatrics msk systemic 21hydroxylasedeficiency 21ohd alzheimersdisease ankylosingspondylitis bulimianervosa caudaequina dementia endocrinology fecal gastrointestinal
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
- Budd Chiari Syndrome ... Erythematosus #SLE ... Gastrointestinal #Complications ... pathophysiology #signs #symptoms
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... Signs/Symptoms ... /Complications: ... pathophysiology #peds #pediatrics
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Erythematosus (SLE ... Erythematosus #SLE ... Musculoskeletal #Complications ... pathophysiology #signs #symptoms
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
mutations - Down syndrome ... chromosome 21) Signs / Symptoms ... / Complications ... pathophysiology #geriatrics ... diagnosis #signs #symptoms
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
Primary Sjogren’s Syndrome ... Sjögren's, the syndrome ... erythematosus (SLE ... ) Signs / Symptoms ... Diagnosis #Signs #Symptoms
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... spine Signs / Symptoms ... / Complications ... #CaudaEquina #Syndrome ... pathophysiology #diagnosis #symptoms
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children) Upper Respiratory Tract Infection: - Bacterial: Streptococcus
resolve by 72 hours Complications ... seizures, abscess (see ... pathophysiology #diagnosis #symptoms ... #signs #peds #pediatrics
Fecal Incontinence - Pathogenesis and Complications Continence mechanisms are impaired • Local neuronal damage • External and
Pathogenesis and Complications ... irritable bowel syndrome ... #Incontinence #geriatrics
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Phenomenon #Lupus #SLE ... diagnosis #signs #symptoms ... #complications
Upper Urinary Tract infection (UUTI): Pathogenesis and Clinical Findings Predisposing Factors: - Immunocompromised, Diabetes, - Elderly, Female
lower tract: As a complication ... bacteriuria or cystitis (see ... Pathophysiology #Signs #Symptoms
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