The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis pathophysiology signs behavioraldisorder criteria mnemonic personalitydisorder mooddisorders riskfactors syndrome 21hydroxylasedeficiency 21ohd alcoholusedisorder amsuicide anorexianervosa aseptic bipolar borderline bpd bulimianervosa
Obsessive-Compulsive Disorder (OCD): Pathogenesis and clinical findings Psychological Hypothesis • Cognitive behavioral model: Emotional disturbance arising from
maladaptive beliefs and anxiety ... Dysregulation of anxiety ... regions suspected Genetics ... PersonalityDisorder #Diagnosis #Psychiatry ... #Signs #Symptoms
Pathogenesis of Anxiety Disorders Anxiety Disorders: A maladaptive emotional state causing fear, worry, and excessive stress, characterized by:
Pathogenesis of Anxiety ... Disorders Anxiety ... reporting rates) • Genetics ... acid (GABA) #Anxiety ... Pathophysiology #diagnosis #psychiatry
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Syndrome Signs/Symptoms ... PraderWilli #Syndrome #genetics ... pathophysiology #peds ... #pediatrics
Post-Traumatic Stress Disorder (PTSD) Neurochemical abnormalities • Hyper-vigilance • Emotional hyper-arousal • Exaggerated startle reflex • Anxiety
startle reflex • Anxiety ... Pathophysiology #diagnosis #symptoms ... #signs #psychiatry
Panic Disorder: Pathogenesis and clinical findings Social Factors • Parenting and infant attachment • Childhood illness/abuse •
Neurotic personality Genetics ... carrying anti-anxiety ... Anticipatory Anxiety ... PanicDisorder #Anxiety ... #signs #psychiatry
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings Symptoms (included in DSM 5 criteria) - Present during
Clinical Findings Symptoms ... suicide Other Symptoms ... partum onset) - Anxiety ... Pathophysiology #Signs #Symptoms ... #Psychiatry
Alcohol Use Disorder: Pathogenesis and Clinical Findings • Tolerance (reduced sensitivity to effects of EtOH) •
• Withdrawal symptoms ... , seizure, and anxiety ... Diagnosis #Signs #Symptoms ... #Psychiatry
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... pathophysiology #genetics ... endocrinology #peds ... #pediatrics
Bipolar Disorder: Pathogenesis and Clinical Findings • Disruption of emotional homeostasis • Oscillation between mood states
- Incr guilt, anxiety ... Pathophysiology #Signs #Symptoms ... #Psychiatry
Borderline Personality Disorder: Pathogenesis and Clinical Findings Behavioral Traits: • Unstable Relationships - Alternating extremes of idealization
severe dissociative symptoms ... / irritability/anxiety ... the above with symptoms ... PersonalityDisorder #Diagnosis #Psychiatry ... Criteria #Signs #Symptoms
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