The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
StressDisorder #PTSD #BehavioralDisorder ... Pathophysiology #diagnosis #symptoms ... #signs #psychiatry
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
Depressive Disorder (MDD ... Clinical Findings Symptoms ... suicide Other Symptoms ... Pathophysiology #Signs ... #Symptoms #Psychiatry
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
have either 26 symptoms ... at > 17 years old ... 2 settings - Symptoms ... AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... #signs #psychiatry
Obsessive-Compulsive Disorder (OCD): Pathogenesis and clinical findings

Psychological Hypothesis
 • Cognitive behavioral model: Emotional disturbance arising from
Obsessive-Compulsive Disorder (OCD ... Obsessive-Compulsive Disorder (OCD ... PersonalityDisorder #Diagnosis #Psychiatry ... #Signs #Symptoms
Panic Disorder: Pathogenesis and clinical findings
Social Factors
 • Parenting and infant attachment
 • Childhood illness/abuse
 •
trigger Physical Symptoms ... Psychological Symptoms ... Uncontrollable fear about symptoms ... PanicDisorder #Anxiety #BehavioralDisorder ... #signs #psychiatry
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Deficiency (21-OHD ... degrees of 21-OHD ... Signs/Symptoms/Complications ... endocrinology #peds
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children)
Upper Respiratory Tract Infection: 
 - Bacterial: Streptococcus
Acute Otitis Media ... pathophysiology #diagnosis #symptoms ... #signs #peds #pediatrics
Oppositional Defiant Disorder (ODD): Pathogenesis and clinical findings
 - Must have >4 symptoms for >6 months,
Defiant Disorder (ODD ... developmental level - ODD ... 3 settings - ODD ... #BehavioralDisorder ... #signs #psychiatry
Social Anxiety Disorder (SAD) - Pathophysiology 
Excessive fear of one or more social situations
 • Safety
• Behavioral Symptoms ... • Cognitive Symptoms ... derealization • Physical Symptoms ... SocialAnxiety #BehavioralDisorder ... #signs #psychiatry
Conduct Disorder (CD): Pathogenesis and clinical findings
 - Must have >3 symptoms present in the past
- Must have >3 symptoms ... months, with >1 symptom ... individual is >18 years old ... #Conduct #CD #BehavioralDisorder ... #signs #psychiatry