The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
Pituitary Mass Effects ... Pituitary adenomas ... • For pituitary ... Signs / Symptoms ... #SideEffects #endocrinology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
production by the pituitary ... Signs/Symptoms: ... Hyperthyroidism #endocrinology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... #FeedbackLoop #endocrinology ... pathophysiology #pituitary
Cubital Tunnel Syndrome: Pathogenesis and clinical findings

 • Paresthesia of 5th and medial half of 4th
Cubital Tunnel Syndrome ... test • + Tinel sign ... • + Froment's sign ... CubitalTunnel #Syndrome ... #symptoms #msk
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
the etiology Signs ... /Symptoms: - Pretibial ... pathophysiology #endocin #endocrinology ... #symptoms #signs
Obsessive-Compulsive Disorder (OCD): Pathogenesis and clinical findings

Psychological Hypothesis
 • Cognitive behavioral model: Emotional disturbance arising from
ObsessiveCompulsive #PersonalityDisorder ... Diagnosis #Psychiatry #Signs ... #Symptoms
Patellofemoral Syndrome - Pathogenesis and clinical findings
 • Anterior Knee Pain with possible symptoms of 'catching'
Patellofemoral Syndrome ... with possible symptoms ... Patellofemoral #Syndrome ... pathophysiology #diagnosis #signs ... #symptoms #msk
Menstrual Cycle Physiology: Ovarian Cycle – Follicular Phase Explained
Early Follicular Phase (Days 0-5)
 • Granulosa cells
production by pituitary ... back on anterior pituitary ... production by pituitary ... Polycystic Ovarian Syndrome ... FollicularPhase #endocrinology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Primary Sjogren’s Syndrome ... erythematosus (SLE) Signs ... / Symptoms: - ... Pathophysiology #Diagnosis #Signs ... #Symptoms
Borderline Personality Disorder: Pathogenesis and Clinical Findings
Behavioral Traits:
 • Unstable Relationships - Alternating extremes of idealization
severe dissociative symptoms ... the above with symptoms ... BPD #Borderline #PersonalityDisorder ... Psychiatry #Criteria #Signs ... #Symptoms #Mnemonic