The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
#Pharmacology #SideEffects ... Psychiatry #Diagnosis #Signs ... #Symptoms
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
the etiology Signs ... /Symptoms: - Pretibial ... pathophysiology #endocin #endocrinology ... #symptoms #signs
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
#Pharmacology #SideEffects ... Psychiatry #Diagnosis #Signs ... #Symptoms
Schizotypal Personality Disorder (SPD): Pathogenesis and clinical findings
Cognitive-Perceptual
 • Magical thinking - Belief in paranormal or
Personality Disorder (SPD ... familiarity SPD ... impairment #SPD ... Diagnosis #Psychiatry #Criteria ... #Signs #Symptoms
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Signs/Symptoms: ... Hyperthyroidism #endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
Signs / Symptoms ... #Macroadenoma #SideEffects ... #endocrinology
Antisocial Personality Disorder (ASPD): Pathogenesis and Clinical Findings
Work & lnterpersonal:
 • Home Life Troubles - Conflict
Personality Disorder (ASPD ... physical assault ASPD ... bipolar disorder #ASPD ... Diagnosis #Psychiatry #Criteria ... #Signs #Symptoms
Avoidant Personality Disorder (AVPD): Pathogenesis and Clinical Findings
 • Restraint - Shows excessive restraint in intimate
Personality Disorder (AVPD ... inferior to others AVPD ... or inferior #AVPD ... Diagnosis #Psychiatry #Criteria ... #Signs #Symptoms
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
Clinical Findings Symptoms ... included in DSM 5 criteria ... suicide Other Symptoms ... Pathophysiology #Signs ... #Symptoms #Psychiatry
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... #FeedbackLoop #endocrinology