The Calgary Guide to Understanding Disease @TheCalgaryGuide
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sle erythematosus orthopedics psychiatry systemic achilles anorexianervosa caudaequina cecs chronicexertional compartmentsyndrome depression disease femoralhead fractures gastrointestinal kawasaki majordepressivedisorder manifestations mdd
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Erythematosus #SLE #MSK ... Musculoskeletal #Complications ... #pathophysiology ... #signs #symptoms ... #diagnosis
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... Gastrointestinal #Complications ... #pathophysiology ... #signs #symptoms ... #diagnosis
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... /Symptoms/Complications ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology ... #signs #symptoms
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
/Symptoms/Complications ... TendonRupture #diagnosis ... #signs #symptoms ... #pathophysiology ... #msk #orthopedics
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings Symptoms (included in DSM 5 criteria) - Present during
included in DSM 5 criteria ... thoughts of death or suicide ... MoodDisorders #Diagnosis ... #Pathophysiology ... #Signs #Symptoms
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
/ Symptoms / Complications ... CaudaEquina #Syndrome #MSK ... #pathophysiology ... #diagnosis #symptoms ... #signs
Kawasaki Disease: Clinical Findings Diagnostic Criteria - Fever and 4/5 of the following: • Conjunctivitis • Polymorphous
Clinical Findings Diagnostic ... Criteria - Fever ... /Symptoms/Complications ... #Diagnosis #Pathophysiology ... #Signs #Symptoms
Chronic Exertional Compartment Syndrome (CECS) • Diagnosis Of CECS requires patient to undergo the same exertional
• Diagnostic ... criteria for CECS ... CompartmentSyndrome #CECS #pathophysiology ... #diagnosis #signs ... #symptoms #msk
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... bone formation MSK ... PagetsDisease #pathophysiology ... #diagnosis #signs ... #symptoms #complications
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