The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... spinal artery injury ... weakness and #Acute ... pathophysiology #signs #symptoms ... #msk #orthopedics
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
the pancreas, Vasculitis ... -> Acute Pancreatitis ... pathophysiology #signs #symptoms
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Acute Rheumatic ... cells -> Tissue injury ... Pancarditis and valvular injury ... , Carditis #Acute ... diagnosis #signs #symptoms
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
blood vessels (vasculitis ... pathophysiology #signs #symptoms ... #diagnosis #ExtraArticular
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Avulsion or shearing injury ... lateral hip Signs/Symptoms ... pathophysiology #signs #symptoms ... #orthopedics
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
warriors") • Acute ... etiology Signs/Symptoms ... diagnosis #signs #symptoms ... pathophysiology #msk #orthopedics
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
causes direct injury ... Diagnosis #Signs #Symptoms ... #Vasculitis
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
to glenoid -> Acute ... Diagnosis #signs #symptoms ... #msk #orthopedics
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
Inflammation: Incr tissue injury ... emptying - Voiding Symptoms ... Hydronephrosis, Acute ... chronic renal injury ... Urology #Signs #Symptoms
Takayasu’s Arteritis: Pathogenesis and clinical findings

 - Fatigue, weight loss, low grade fever, arthralgias
 - Incr
, Incr risk of Acute ... Takayasus #Arteritis #Vasculitis ... Diagnosis #Signs #Symptoms