The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis pathophysiology msk complications sle achilles anterior arteritis avascularnecrosis benign bph erythematosus femoralhead fractures gastrointestinal hyperplasia manifestations mucocutaneous neurology pan
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... -> Acute Pancreatitis ... pathophysiology #signs ... #symptoms #diagnosis
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Posterior hip dislocation ... • Anterior hip dislocation ... Avulsion or shearing injury ... onto lateral hip Signs ... #symptoms #orthopedics
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... weakness and #Acute ... pathophysiology #signs ... #symptoms #msk ... #orthopedics #neurology
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
Anterior Shoulder Dislocation ... to glenoid -> Acute ... #Diagnosis #signs ... #symptoms #msk ... #orthopedics #pathophysiology
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
Acute Rheumatic ... cells -> Tissue injury ... , Carditis #Acute ... pathophysiology #diagnosis #signs ... #symptoms #complications
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis #signs ... #symptoms #complications
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
warriors") • Acute ... pre-determined etiology Signs ... /Symptoms/Complications ... #symptoms #pathophysiology ... #msk #orthopedics
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
causes direct injury ... Pathophysiology #Diagnosis #Signs ... #Symptoms #Vasculitis
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings Hormonal alterations (result of aging process) ->
Inflammation: Incr tissue injury ... Hydronephrosis, Acute ... chronic renal injury ... Pathophysiology #Urology #Signs ... #Symptoms #Diagnosis
Avascular Necrosis: Pathogenesis and Clinical Findings • Physical Trauma (esp. to the scaphoid bone with damage
therapy - Lupus ... affected) - Acute ... hypolucency "Crescent sign ... pathophysiology #diagnosis #signs ... #symptoms
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