The Calgary Guide to Understanding Disease @TheCalgaryGuide
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signs pathophysiology complications arteritis lupus sle erythematosus extraarticular giantcell ra rheumatoidarthritis systemic ankylosingspondylitis avascularnecrosis cranialarteritis gastrointestinal giantcellarteritis mastoiditis msk mucocutaneous
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
Giant Cell (Temporal ... old; F>M Signs/Symptoms ... Pathophysiology #Diagnosis ... #Signs #Symptoms ... #Vasculitis
Giant Cell (Temporal) Arteritis: Clinical findings and Complications Signs/Symptoms: - Headache (usually constant, superimposed by waves
Giant Cell (Temporal ... Complications Signs/Symptoms ... palpation - Temporal ... #GiantCell #Temporal ... #diagnosis #Vasculitis
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Gastrointestinal Manifestations ... the pancreas, Vasculitis ... -> Acute Pancreatitis ... pathophysiology #signs #symptoms ... #diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Musculoskeletal Manifestations ... Esp. humeral and femoral ... pathophysiology #signs #symptoms ... #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Mucocutaneous Manifestations ... Livedo Reticularis, Vasculitis ... Mucocutaneous #Manifestations ... pathophysiology #diagnosis ... #signs #symptoms
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
swelling - GI Manifestations ... Pathophysiology #Diagnosis ... #Signs #Symptoms ... #Vasculitis
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Extra-articular manifestations ... blood vessels (vasculitis ... pathophysiology #signs #symptoms ... #diagnosis #ExtraArticular
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
clinical findings Acute ... portion of the temporal ... sinus thrombosis, Temporal ... pathophysiology #signs #symptoms ... #diagnosis #otology
Giant Cell Arteritis (Polymyalgia Rheumatica and Cranial Arteritis): Pathogenesis and Clinical Findings - Morning Stiffness (>1
Weight Loss #Temporal ... Pathophysiology #Signs #Symptoms ... #Diagnosis #Vasculitis
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Extra-articular manifestations ... • Non-specific Acute-phase ... pathophysiology #signs #symptoms ... #diagnosis
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