The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology symptoms erythematosus lupus orthopedics peds systemic alzheimersdisease ankylosingspondylitis caudaequina classification dementia femoralhead gastrointestinal genetics geriatrics grades grading musculoskeletal otitismedia
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
of Pelvic Ring Fractures ... and Complications ... Anterior Sl diastasis ... #Orthopedics #MSK ... #diagnosis #complications
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... onto lateral hip Signs ... /Symptoms/Complications ... #msk #diagnosis ... pathophysiology #signs
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... Signs/Symptoms ... /Complications: ... Incr Skeletal fractures ... pathophysiology #peds #pediatrics
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Erythematosus (SLE ... #MSK #Musculoskeletal ... #Complications ... pathophysiology #signs ... #symptoms #diagnosis
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
- Budd Chiari Syndrome ... Erythematosus #SLE ... Gastrointestinal #Complications ... pathophysiology #signs ... #symptoms #diagnosis
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... / Symptoms / Complications ... #MSK #pathophysiology ... #diagnosis #symptoms ... #signs
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... / Symptoms / Complications ... pathophysiology #geriatrics ... #diagnosis #signs
Ankylosing Spondylitis: Pathogenesis and Clinical findings • Pain in lumbar area and gluteal region: (Dull, insidious
pseudo-widening in Sl ... column) • Late complication ... bamboo spine) -> Fracture ... pathophysiology #diagnosis ... #signs #symptoms
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children) Upper Respiratory Tract Infection: - Bacterial: Streptococcus
resolve by 72 hours Complications ... seizures, abscess (see ... pathophysiology #diagnosis ... #symptoms #signs ... #peds #pediatrics
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... bone formation MSK ... -> Pathologic fractures ... pathophysiology #diagnosis ... #signs #symptoms
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