The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology vasculitis complications erythematosus lupus msk rheumatoidarthritis systemic temporal cecs chronicexertional compartmentsyndrome disease extraarticular gastrointestinal henochscholeinpurpura hsp iga kawasaki musculoskeletal
Giant Cell (Temporal) Arteritis: Clinical findings and Complications Signs/Symptoms: - Headache (usually constant, superimposed by waves
Cell (Temporal) Arteritis ... Complications Signs ... Hemorrhages #GiantCell ... Complications #Signs ... #Symptoms #diagnosis
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
like rheumatoid arthritis ... (RA) or systemic ... erythematosus (SLE ... ) Signs / Symptoms ... #Signs #Symptoms
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
Cell (Temporal) Arteritis ... yrs old; F>M Signs ... neurological findings #GiantCell ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Erythematosus (SLE ... - Arthralgia, Arthritis ... Erythematosus #SLE ... pathophysiology #signs ... #symptoms #diagnosis
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
- Budd Chiari Syndrome ... Erythematosus #SLE ... pathophysiology #signs ... #symptoms #diagnosis
Psoriatic Arthritis: Pathogenesis and Clinical findings In tendons and connective tissues: • Enthesitis - Pain/tenderness over
Psoriatic Arthritis ... Arthritis of DIP ... polyarthritis (like RA ... pathophysiology #diagnosis ... #signs #symptoms
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis ... (RA): Extra-articular ... effusion on CXR • RA ... pathophysiology #signs ... #symptoms #diagnosis
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Rheumatoid arthritis ... (RA): Pathogenesis ... Extra-articular signs ... pathophysiology #signs ... #symptoms #diagnosis
Kawasaki Disease: Clinical Findings Diagnostic Criteria - Fever and 4/5 of the following: • Conjunctivitis • Polymorphous
Clinical Findings Diagnostic ... Criteria - Fever ... hands & feet Signs ... : - Coronary Arteritis ... #Signs #Symptoms
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
nephrotic/nephritic syndrome ... Arthralgia's (common), arthritis ... Pathophysiology #Diagnosis ... #Signs #Symptoms
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