The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
startle reflex • Anxiety ... StressDisorder #PTSD #BehavioralDisorder ... Pathophysiology #diagnosis ... #symptoms #signs
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
Clinical Findings Symptoms ... included in DSM 5 criteria ... suicide Other Symptoms ... partum onset) - Anxiety ... MoodDisorders #Diagnosis
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
patients < 50 yrs old ... ; F>M Signs/Symptoms ... Pathophysiology #Diagnosis ... #Signs #Symptoms ... #Vasculitis
Obsessive-Compulsive Disorder (OCD): Pathogenesis and clinical findings

Psychological Hypothesis
 • Cognitive behavioral model: Emotional disturbance arising from
maladaptive beliefs and anxiety ... Dysregulation of anxiety ... reduce obsessional anxiety ... PersonalityDisorder #Diagnosis ... Psychiatry #Signs #Symptoms
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
findings - For diagnosis ... to 25 for new diagnosis ... at > 17 years old ... AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... #psychiatry #criteria
Panic Disorder: Pathogenesis and clinical findings
Social Factors
 • Parenting and infant attachment
 • Childhood illness/abuse
 •
carrying anti-anxiety ... Anticipatory Anxiety ... PanicDisorder #Anxiety ... #BehavioralDisorder ... Pathophysiology #diagnosis
Borderline Personality Disorder: Pathogenesis and Clinical Findings
Behavioral Traits:
 • Unstable Relationships - Alternating extremes of idealization
/ irritability/anxiety ... the above with symptoms ... PersonalityDisorder #Diagnosis ... #Psychiatry #Criteria ... #Signs #Symptoms
Oppositional Defiant Disorder (ODD): Pathogenesis and clinical findings
 - Must have >4 symptoms for >6 months,
Defiant Disorder (ODD ... develop mood and anxiety ... #BehavioralDisorder ... Pathophysiology #diagnosis ... #psychiatry #criteria
Schizotypal Personality Disorder (SPD): Pathogenesis and clinical findings
Cognitive-Perceptual
 • Magical thinking - Belief in paranormal or
anhedonia • Social Anxiety ... reference - Anxiety ... PersonalityDisorder #Diagnosis ... #Psychiatry #Criteria ... #Signs #Symptoms
Social Anxiety Disorder (SAD) - Pathophysiology 
Excessive fear of one or more social situations
 • Safety
Social Anxiety Disorder ... of Anxiety: Mind ... SocialAnxiety #BehavioralDisorder ... Pathophysiology #diagnosis ... #symptoms #signs