The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis signs symptoms msk orthopedics sports complications fractures grading acute allergic allergy benign bph definitions glaucoma grades hyperplasia hypersensitivity
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
below level of injury ... spinal artery injury ... below level of injury ... tumour causing injury ... #orthopedics #neurology
Open Fractures: Mechanisms, Clinical Features and Complications Gustilo-Anderson Classification: • Type I - Wound <
Gustilo-Anderson Classification ... Typically "inside out" injury ... GustiloAnderson #Classification
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
Classification of ... possible vascular injury ... - Type 1 or 2 injury ... PelvicRing #Fractures #Classification
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
cells -> Tissue injury ... Pancarditis and valvular injury
Posterior Cruciate Ligament (PCL) Injury: Pathogenesis and Clinical Findings Classification of PCL Iniuries • Partial: Translation <
Ligament (PCL) Injury ... Clinical Findings Classification ... PCL: The PCL is injured ... PosteriorCruciateLigament #PCL #Injury ... pathophysiology #classification
Myelopathy - Injury to the entire spinal cord - Signs and Symptoms • Ataxia (early sign)
Myelopathy - Injury
Low Ankle Sprain: Pathomechanics and Clinical Findings Grading Ligament Sprains l: Minimal ligament disruption, mild swelling & tenderness,
most commonly injured ... the CFL is also injured ... (uncommonly injured ... PTFL is rarely injured
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Reactions #Types #Classification
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Avulsion or shearing injury
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
causes direct injury
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