The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology signs symptoms complications sle arteritis msk systemic temporal allergic allergy classification definitions degenerative gastrointestinal hypersensitivity inflammatory jointdisease jointpain manifestations
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... #Systemic #Lupus ... #Erythematosus ... signs #symptoms #diagnosis
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
palpation - Vasculitic ... neurological findings #GiantCell ... Pathophysiology #Diagnosis ... Signs #Symptoms #Vasculitis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... #Systemic #Lupus ... #Erythematosus ... signs #symptoms #diagnosis
Giant Cell (Temporal) Arteritis: Clinical findings and Complications Signs/Symptoms: - Headache (usually constant, superimposed by waves
Hemorrhages #GiantCell ... Signs #Symptoms #diagnosis ... #Vasculitis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... Livedo Reticularis, Vasculitis ... Phenomenon #Lupus ... pathophysiology #diagnosis
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
• Ex: Systemic Lupus ... Erythematosus, ... Classification #Diagnosis
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
RA) or systemic lupus ... erythematosus ( ... Pathophysiology #Diagnosis
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
Rheumatoid arthritis, Lupus ... #Degenerative #Comparison ... JointDisease #JointPain #Diagnosis
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