The Calgary Guide to Understanding Disease @TheCalgaryGuide
564.5K 396 156
Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
Contributor Ranks
Latest Searches
15 results
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
: Gastrointestinal ... the pancreas, Vasculitis ... #Complications ... pathophysiology #signs #symptoms ... #diagnosis
Giant Cell (Temporal) Arteritis: Clinical findings and Complications
Signs/Symptoms: 
 - Headache (usually constant, superimposed by waves
Clinical findings and Complications ... Signs/Symptoms ... Hemorrhages #GiantCell ... Temporal #Arteritis #Complications ... #diagnosis #Vasculitis
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
old; F>M Signs/Symptoms ... neurological findings #GiantCell ... Pathophysiology #Diagnosis ... #Signs #Symptoms ... #Vasculitis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Osteonecrosis Esp ... Musculoskeletal #Complications ... pathophysiology #signs #symptoms ... #diagnosis
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis ... #signs #symptoms ... #complications
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
IgA Vasculitis – ... (100%) - Gastrointestinal ... and ankles) #HSP ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
• Posterior hip ... Signs/Symptoms ... /Complications: ... Fractures #msk #diagnosis ... pathophysiology #signs #symptoms
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
Inflammation of skin (esp ... blood vessels (vasculitis ... blood to limbs (esp ... pathophysiology #signs #symptoms ... #diagnosis #ExtraArticular
Opioid Withdrawal: Clinical Findings and Complications
Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
Clinical Findings and Complications ... Symptoms can take ... myalgias) - Gastrointestinal ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
primarily deltoids and hip ... Polymyositis #PM #Diagnosis ... Pathophysiology #Signs #Symptoms ... #Vasculitis