The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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signs pathophysiology complications temporal arteritis erythematosus syndrome systemic acute adhesivecapsulitis caudaequina cranialarteritis dermatomyositis dm frozenshoulder gastrointestinal giantcellarteritis injury manifestations mucocutaneous
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... Erythematosus #SLE ... pathophysiology #signs #symptoms ... #diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... #MSK #Musculoskeletal ... pathophysiology #signs #symptoms ... #diagnosis
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
old; F>M Signs/Symptoms ... neurological findings #GiantCell ... Pathophysiology #Diagnosis ... #Signs #Symptoms ... #Vasculitis
Giant Cell (Temporal) Arteritis: Clinical findings and Complications Signs/Symptoms: - Headache (usually constant, superimposed by waves
Complications Signs/Symptoms ... Stroke or TIA-like symptoms ... Hemorrhages #GiantCell ... Complications #Signs #Symptoms ... #diagnosis #Vasculitis
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
RA) or systemic lupus ... erythematosus (SLE ... ) Signs / Symptoms ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Livedo Reticularis, Vasculitis ... #SLE #Mucocutaneous ... pathophysiology #diagnosis ... #signs #symptoms
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
spine Signs / Symptoms ... reflexes) • Urinary ... CaudaEquina #Syndrome #MSK ... pathophysiology #diagnosis ... #symptoms #signs
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Bladder retention -> Primarily ... hemicord lesion -> Primarily ... Injury #Syndromes #diagnosis ... pathophysiology #signs #symptoms ... #msk #orthopedics
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Subacute development, primarily ... Polymyositis #PM #Diagnosis ... Pathophysiology #Signs #Symptoms ... #Vasculitis
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
Findings • Primary ... pathophysiology #diagnosis ... #symptoms #signs ... stages #staging #msk
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