Pathnologic @pathnologic
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The many faces of the Hodgkin/Reed-Sternberg (HRS) cell: Even as medical students we are aware of
lymphoma. ... Many variants exist ... #Lymphoma #ReedSternberg ... cell #Pathology #Clinical ... #Microscopy
A morphologic mosaic of NUT carcinoma: monotonous primitive cells, basophilic to clear cytoplasm, abrupt keratinization, prominent
mosaic of NUT carcinoma ... -NUT fusion or variants ... LisaRooperMD #NUT #carcinoma ... #Pathology #Clinical ... #Microscopy #Mosaic
Hobnail variant of PTC: micropapillary architecture, dense eosinophilic cytoplasm, hobnail cells with apical nuclei, and marked
Hobnail variant ... Papillary #Thyroid #Carcinoma ... #Pathology #Clinical ... #Microscopy
Oncocytic Variant of Medullary Carcinoma
Don't assume every oncocytic thyroid tumor is a Hurthle cell neoplasm! Nested
Oncocytic Variant ... of Medullary Carcinoma ... for oncocytic variant ... #Pathology #Microscopy ... #Clinical
SMARCB1-deficient sinonasal carcinoma: high grade tumors with varying proportions of basaloid and plasmacytoid/rhabdoid cells; CK+, SMARCB1
deficient sinonasal carcinoma ... synapto; aggressive clinical ... deficient #sinonasal #Carcinoma ... #Pathology #Microscopy ... #Clinical
Salivary acinic cell carcinoma is usually an H&E diagnosis for me- but this zymogen-granule poor variant
Salivary acinic cell carcinoma ... zymogen-granule poor variant ... #Acinic #Cell #Carcinoma ... #Pathology #Microscopy ... #Clinical
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
to medium size lymphoid ... Peripheral #Pathology #Microscopy ... #Clinical #Blood
Here is a lymph node that is lymphoid-depleted, fibrotic, and burned-out, typical of late phase HIV
lymph node that is lymphoid-depleted ... Lymphadenitis: - Marked lymphoid ... PatternC #Pathology #Microscopy ... #LymphNode #Clinical
Diffuse Sclerosis Variant—PTC 
 - Rare variant of PTC 
 - Approximately 3% ofall PTC
Diffuse Sclerosis Variant—PTC ... - Rare variant ... Cytology: • Carcinoma ... Cancer #Pathology #Clinical ... #Gross #Microscopy
Morphologic spectrum of salivary secretory carcinoma: microcystic or papillary-cystic architecture, abundant eosinophilic vacuolated cytoplasm, bubbly luminal
salivary secretory carcinoma ... salivary #secretory #carcinoma ... #Pathology #Clinical ... #Microscopy