Pathnologic @pathnologic
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Post-splenectomy blood smear demonstrating Howell-Jolly bodies and target cells.

#Clinical #Pathology #BloodSmear #HowellJollyBodies #TargetCells #Splenectomy #Asplenic
demonstrating Howell-Jolly bodies ... and target cells ... #Clinical #Pathology ... #Splenectomy #Asplenic
Herpes Simplex Virus 
Lymphadenitis 
 • Expanded paracortex 
 • HSV-infected cells are 
present in areas
• HSV-infected cells ... are present in ... Lymphadenitis #HSV #Pathology ... #Microscopy #Clinical ... #LymphNode
Paracoccidioides brasiliensis Lymphadenitis: 

Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in
Head&neck, Lymph Nodes ... , and lungs are ... seen within giant cells ... Lymphadenitis #Pathology ... #LymphNode #Clinical
Howell-Jolly Body - On these Wright-stained peripheral blood smears the small dark spheres within red cells
bodies. ... These bodies represent ... Howell-Jolly bodies ... #Clinical #Path ... Howell #Jolly #Asplenia
Aldosteronoma — Spironolactone Bodies 

1. Spironolactone is often used to treat hypertension caused by hyperaldosteronism, and
Spironolactone Bodies ... SBI are often small ... Red blood cells ... endoplasmic reticulum in cells ... #Pathology #Clinical
Amiodarone induced thyroid changes

Histopath: Remarkably enlarged follicles, distended with colloid, without 
scalloping, and lined by flattened
Amiodarone induced thyroid ... flattened follicular cells ... There are two types ... thyrotoxicosis #AIT #Pathology ... #Clinical #Microscopy
Neoplastic plasma cells with nucleoli (left image) and intranuclear Dutcher body (right image).

Dutcher bodies are round,
Neoplastic plasma cells ... Dutcher bodies are ... #DutcherBody #Bodies ... #Intranuclear #Pathology ... #Clinical #Smear
Diffuse Sclerosis Variant—PTC 
 - Rare variant of PTC 
 - Approximately 3% ofall PTC
• Carcinoma cells ... Numerous psammoma bodies ... PTC #Papillary #Thyroid ... #Cancer #Pathology ... #Clinical #Gross
Grouped Pustules on an Erythematous Base - On physical examination, grouped, coalescing pustules that had scalloped
seen on the left arm ... multinucleated giant cells ... #Clinical #Derm ... #Pathology #Herpes ... Smear #Microscopy #NEJM
Glucagonoma-Associated Rash - The rash involved the arms, genitals, and buttocks and had progressed to the
rash involved the arms ... tissue revealed a well-circumscribed ... resolve (Panel D) #Clinical ... #HONC #Derm #Pathology ... Microscopy #CT #NEJM