Pathnologic @pathnologic
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Post-splenectomy blood smear demonstrating Howell-Jolly bodies and target cells.

#Clinical #Pathology #BloodSmear #HowellJollyBodies #TargetCells #Splenectomy #Asplenic
bodies and target cells ... #Clinical #Pathology ... #BloodSmear #HowellJollyBodies
Herpes Simplex Virus 
Lymphadenitis 
 • Expanded paracortex 
 • HSV-infected cells are 
present in areas
Simplex Virus Lymphadenitis ... • HSV-infected cells ... Simplex #Virus #Lymphadenitis ... #HSV #Pathology ... #Microscopy #Clinical
Paracoccidioides brasiliensis Lymphadenitis: 

Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in
Paracoccidioides brasiliensis Lymphadenitis ... seen within giant cells ... #brasiliensis #Lymphadenitis ... #Pathology #LymphNode ... #Clinical #Microscopy
Squamous-Cell Carcinoma of the Tongue - Intraoral examination revealed a well-circumscribed superficial ulcer, with a homogeneous
Squamous-Cell Carcinoma ... invasive squamous-cell ... carcinoma (Panel B) #Clinical ... #Pathology #Honc ... Squamous #Microscopy #NEJM
A – cabot ring, B – Howell-Jolly Body

What are Cabot’s rings?
- They are delicate threadlike inclusions
the red blood cells ... #Clinical #Pathology ... #Microscopy #BloodSmear
Hobnail variant of PTC: micropapillary architecture, dense eosinophilic cytoplasm, hobnail cells with apical nuclei, and marked
cytoplasm, hobnail cells ... PTC #Papillary #Thyroid ... #Carcinoma #Pathology ... #Clinical #Microscopy
Amiodarone induced thyroid changes

Histopath: Remarkably enlarged follicles, distended with colloid, without 
scalloping, and lined by flattened
Amiodarone induced thyroid ... flattened follicular cells ... change, Follicular cells ... thyrotoxicosis #AIT #Pathology ... #Clinical #Microscopy
Here is a lymph node with florid follicular hyperplasia typical of HIV lymphadenitis (so-called "pattern A",
typical of HIV lymphadenitis ... Warthin-Finkeldey type giant cells ... Monocytoid B cells ... #PatternA #Pathology ... Microscopy #LymphNode #Clinical
Glucagonoma-Associated Rash - The rash involved the arms, genitals, and buttocks and had progressed to the
tissue revealed a well-circumscribed ... resolve (Panel D) #Clinical ... #HONC #Derm #Pathology ... Microscopy #CT #NEJM
Oncocytic Variant of Medullary Carcinoma
Don't assume every oncocytic thyroid tumor is a Hurthle cell neoplasm! Nested
every oncocytic thyroid ... tumor is a Hurthle cell ... Medullary #Carcinoma #Pathology ... #Microscopy #Clinical