Pathnologic @pathnologic
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Beautiful acanthocytes/spur cells in a patient with McLeod Syndrome. X-linked disorder characterized by reduced expression of
acanthocytes/spur cells ... patient with McLeod Syndrome ... SpurCells #McLeod #Syndrome ... #Smear #Pathology ... #Microscopy #Clinical
Squamous-Cell Carcinoma of the Tongue - Intraoral examination revealed a well-circumscribed superficial ulcer, with a homogeneous
Squamous-Cell Carcinoma ... invasive squamous-cell ... carcinoma (Panel B) #Clinical ... #Pathology #Honc ... Squamous #Microscopy #NEJM
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear
Amiodarone induced thyroid changes

Histopath: Remarkably enlarged follicles, distended with colloid, without 
scalloping, and lined by flattened
Amiodarone induced thyroid ... flattened follicular cells ... change, Follicular cells ... thyrotoxicosis #AIT #Pathology ... #Clinical #Microscopy
Hobnail variant of PTC: micropapillary architecture, dense eosinophilic cytoplasm, hobnail cells with apical nuclei, and marked
cytoplasm, hobnail cells ... PTC #Papillary #Thyroid ... #Carcinoma #Pathology ... #Clinical #Microscopy
Glucagonoma-Associated Rash - The rash involved the arms, genitals, and buttocks and had progressed to the
tissue revealed a well-circumscribed ... resolve (Panel D) #Clinical ... #HONC #Derm #Pathology ... Microscopy #CT #NEJM
Oncocytic Variant of Medullary Carcinoma
Don't assume every oncocytic thyroid tumor is a Hurthle cell neoplasm! Nested
every oncocytic thyroid ... tumor is a Hurthle cell ... Medullary #Carcinoma #Pathology ... #Microscopy #Clinical
Dubin-Johnson Syndrome - A laparoscopic exploration revealed a smooth liver with normal consistency and morphologic features
Dubin-Johnson Syndrome ... staining (Panel B) #Clinical ... #Pathology #DubinJohnson ... #Syndrome #Microscopy ... #NEJM
Perirenal Extramedullary Hematopoiesis - Magnetic resonance imaging of the abdomen, performed without the administration of contrast
hematopoiesis #cilnical ... #Radiology #Pathology ... #Honc #MRI #PerirenalExtramedullaryHematopoiesis ... ExtramedullaryHematopoiesis #Microscopy #NEJM
Diffuse Sclerosis Variant—PTC 
 - Rare variant of PTC 
 - Approximately 3% ofall PTC
• Carcinoma cells ... around the tumor cells ... PTC #Papillary #Thyroid ... #Cancer #Pathology ... #Clinical #Gross