Pathnologic @pathnologic
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Path Geek - All things #pathology
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Herpes Simplex Virus 
Lymphadenitis 
 • Expanded paracortex 
 • HSV-infected cells are 
present in areas
• HSV-infected cells ... Lymphadenitis #HSV #Pathology ... Microscopy #Clinical #LymphNode
Sickle cell anemia and Howell Jolly bodies (nuclear remnants).

 - Dr. Abubaker Elshaikh
@ElshaikhMD

#SickleCell #HowellJolly #Body #Bodies
Sickle cell anemia ... #HowellJolly #Body ... #Bodies #Pathology
Paracoccidioides brasiliensis Lymphadenitis: 

Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in
fibrosis (A) and well-formed ... seen within giant cells ... Lymphadenitis #Pathology ... #LymphNode #Clinical
Signet ring cell histiocytes in lymph node sinuses! This can mimic metastatic adenocarcinoma. Histiocytes have ingested
Signet ring cell ... #SignetRing #Cell ... #Histiocytes #LymphNode ... #Pathology #Clinical
A – cabot ring, B – Howell-Jolly Body

What are Cabot’s rings?
- They are delicate threadlike inclusions
– Howell-Jolly Body ... the red blood cells ... #Clinical #Pathology
Aldosteronoma — Spironolactone Bodies 

1. Spironolactone is often used to treat hypertension caused by hyperaldosteronism, and
spironolactone body ... Red blood cells ... endoplasmic reticulum in cells ... Spironolactone #Bodies #Pathology
Here is a lymph node with florid follicular hyperplasia typical of HIV lymphadenitis (so-called "pattern A",
Warthin-Finkeldey type giant cells ... Monocytoid B cells ... Lymphadenitis #PatternA #Pathology ... #Microscopy #LymphNode
Neoplastic plasma cells with nucleoli (left image) and intranuclear Dutcher body (right image).

Dutcher bodies are round,
Neoplastic plasma cells ... intranuclear Dutcher body ... #Intranuclear #Pathology
Myeloma: In this BM core, most plasma cells contain cytoplasmic immunoglobulin (Russell bodies).

They're difficult to identify
core, most plasma cells ... identify as plasma cells ... RussellBodies #Body ... BoneMarrow #Clinical #Pathology
LAMP2 cardiomyopathy in a 12-year-old boy with sudden death (Table 1; patient #1). A. At autopsy,
LAMP2 cardiomyopathy ... a 12-year-old boy ... cardiac muscle cells ... , or groups of cells ... Clinical #Gross #Pathology