Pathnologic @pathnologic
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Herpes Simplex Virus 
Lymphadenitis 
 • Expanded paracortex 
 • HSV-infected cells are 
present in areas
• HSV-infected cells ... Microscopy #Clinical #LymphNode
Paracoccidioides brasiliensis Lymphadenitis: 

Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in
fibrosis (A) and well-formed ... seen within giant cells ... Lymphadenitis #Pathology #LymphNode
Sickle cell anemia and Howell Jolly bodies (nuclear remnants).

 - Dr. Abubaker Elshaikh
@ElshaikhMD

#SickleCell #HowellJolly #Body #Bodies
Sickle cell anemia ... #HowellJolly #Body
Amiodarone induced thyroid changes

Histopath: Remarkably enlarged follicles, distended with colloid, without 
scalloping, and lined by flattened
Amiodarone induced thyroid ... flattened follicular cells ... change, Follicular cells ... #Amiodarone #thyroid
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
Codocytes (Target cells ... ) - Two target cells ... a Howell-Jolly body ... Target cells are
Signet ring cell histiocytes in lymph node sinuses! This can mimic metastatic adenocarcinoma. Histiocytes have ingested
Signet ring cell ... #SignetRing #Cell ... #Histiocytes #LymphNode
Aldosteronoma — Spironolactone Bodies 

1. Spironolactone is often used to treat hypertension caused by hyperaldosteronism, and
spironolactone body ... Red blood cells ... endoplasmic reticulum in cells
A – cabot ring, B – Howell-Jolly Body

What are Cabot’s rings?
- They are delicate threadlike inclusions
– Howell-Jolly Body ... the red blood cells
Hobnail variant of PTC: micropapillary architecture, dense eosinophilic cytoplasm, hobnail cells with apical nuclei, and marked
cytoplasm, hobnail cells ... PTC #Papillary #Thyroid
Here is a lymph node with florid follicular hyperplasia typical of HIV lymphadenitis (so-called "pattern A",
Warthin-Finkeldey type giant cells ... Monocytoid B cells ... Pathology #Microscopy #LymphNode