Pathnologic @pathnologic
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Diffuse Sclerosis Variant—PTC 
 - Rare variant of PTC 
 - Approximately 3% ofall PTC
• Carcinoma cells ... around the tumor cells ... PTC #Papillary #Thyroid ... #Cancer #Pathology ... #Clinical #Gross
Herpes Simplex Virus 
Lymphadenitis 
 • Expanded paracortex 
 • HSV-infected cells are 
present in areas
• HSV-infected cells ... Lymphadenitis #HSV #Pathology ... Microscopy #Clinical #LymphNode
Here are the morphological hallmarks of Rhabdomyosarcoma.

 - Broken arrow sign 

 - tad-pole rhabdomyoblasts
rhabdomyoblasts - Wraith cells ... - Cross striations ... Rhabdomyosarcoma #Hallmarks #Pathology
The many faces of the Hodgkin/Reed-Sternberg (HRS) cell: Even as medical students we are aware of
Reed-Sternberg (HRS) cell ... Reed-Sternberg cell ... (RS cell). ... Many variants exist ... ReedSternberg #HRS #cell
Hobnail variant of PTC: micropapillary architecture, dense eosinophilic cytoplasm, hobnail cells with apical nuclei, and marked
Hobnail variant ... cytoplasm, hobnail cells ... PTC #Papillary #Thyroid ... #Carcinoma #Pathology
Paracoccidioides brasiliensis Lymphadenitis: 

Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in
fibrosis (A) and well-formed ... seen within giant cells ... Lymphadenitis #Pathology ... #LymphNode #Clinical
Oncocytic Variant of Medullary Carcinoma
Don't assume every oncocytic thyroid tumor is a Hurthle cell neoplasm! Nested
Oncocytic Variant ... every oncocytic thyroid ... tumor is a Hurthle cell ... for oncocytic variant ... Medullary #Carcinoma #Pathology
Signet ring cell histiocytes in lymph node sinuses! This can mimic metastatic adenocarcinoma. Histiocytes have ingested
Signet ring cell ... #SignetRing #Cell ... #Histiocytes #LymphNode ... #Pathology #Clinical
Amiodarone induced thyroid changes

Histopath: Remarkably enlarged follicles, distended with colloid, without 
scalloping, and lined by flattened
Amiodarone induced thyroid ... flattened follicular cells ... change, Follicular cells ... #Amiodarone #thyroid ... thyrotoxicosis #AIT #Pathology
Aldosteronoma — Spironolactone Bodies 

1. Spironolactone is often used to treat hypertension caused by hyperaldosteronism, and
Red blood cells ... endoplasmic reticulum in cells ... Spironolactone #Bodies #Pathology ... #Clinical #Gross