Pathnologic @pathnologic
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Herpes Simplex Virus 
Lymphadenitis 
 • Expanded paracortex 
 • HSV-infected cells are 
present in areas
Simplex Virus Lymphadenitis ... • HSV-infected cells ... Simplex #Virus #Lymphadenitis ... Microscopy #Clinical #LymphNode
Paracoccidioides brasiliensis Lymphadenitis: 

Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in
Paracoccidioides brasiliensis Lymphadenitis ... fibrosis (A) and well-formed ... seen within giant cells ... #brasiliensis #Lymphadenitis ... #Pathology #LymphNode
Here is a lymph node that is lymphoid-depleted, fibrotic, and burned-out, typical of late phase HIV
late phase HIV lymphadenitis ... Pattern C" in HIV Lymphadenitis ... pattern C #HIV #Lymphadenitis ... Pathology #Microscopy #LymphNode
Here is a lymph node with florid follicular hyperplasia typical of HIV lymphadenitis (so-called "pattern A",
typical of HIV lymphadenitis ... Pattern A" in HIV Lymphadenitis ... Warthin-Finkeldey type giant cells ... Monocytoid B cells ... Pathology #Microscopy #LymphNode
Signet ring cell histiocytes in lymph node sinuses! This can mimic metastatic adenocarcinoma. Histiocytes have ingested
Signet ring cell ... #SignetRing #Cell ... #Histiocytes #LymphNode
Squamous-Cell Carcinoma of the Tongue - Intraoral examination revealed a well-circumscribed superficial ulcer, with a homogeneous
Squamous-Cell Carcinoma ... examination revealed a well-circumscribed ... invasive squamous-cell ... Squamous #Microscopy #NEJM
Glucagonoma-Associated Rash - The rash involved the arms, genitals, and buttocks and had progressed to the
tissue revealed a well-circumscribed ... Microscopy #CT #NEJM
Grouped Pustules on an Erythematous Base - On physical examination, grouped, coalescing pustules that had scalloped
multinucleated giant cells ... Smear #Microscopy #NEJM