Pathnologic @pathnologic
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Signet ring cell histiocytes in lymph node sinuses! This can mimic metastatic adenocarcinoma. Histiocytes have ingested
Signet ring cell histiocytes ... Histiocytes have ... SignetRing #Cell #Histiocytes ... #LymphNode #Pathology
Herpes Simplex Virus 
Lymphadenitis 
 • Expanded paracortex 
 • HSV-infected cells are 
present in areas
Microscopy #Clinical #LymphNode
Here is a lymph node that is lymphoid-depleted, fibrotic, and burned-out, typical of late phase HIV
Pathology #Microscopy #LymphNode
Paracoccidioides brasiliensis Lymphadenitis: 

Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in
Lymphadenitis #Pathology #LymphNode
Here is a lymph node with florid follicular hyperplasia typical of HIV lymphadenitis (so-called "pattern A",
Pathology #Microscopy #LymphNode