Pathnologic @pathnologic
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Path Geek - All things #pathology
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Herpes Simplex Virus 
Lymphadenitis 
 • Expanded paracortex 
 • HSV-infected cells are 
present in areas
Herpes Simplex Virus ... • HSV-infected cells ... DennisOMalleyMD) #Herpes #Simplex ... HSV #Pathology #Microscopy ... #Clinical #LymphNode
Here are the morphological hallmarks of Rhabdomyosarcoma.

 - Broken arrow sign 

 - tad-pole rhabdomyoblasts
rhabdomyoblasts - Wraith cells ... - Cross striations ... Hallmarks #Pathology #Microscopy ... #Clinical
The many faces of the Hodgkin/Reed-Sternberg (HRS) cell: Even as medical students we are aware of
Reed-Sternberg cell ... (RS cell). ... Many variants exist ... #Pathology #Clinical ... #Microscopy
Diffuse Sclerosis Variant—PTC 
 - Rare variant of PTC 
 - Approximately 3% ofall PTC
Diffuse Sclerosis ... • Carcinoma cells ... around the tumor cells ... Cancer #Pathology #Clinical ... #Gross #Microscopy
Paracoccidioides brasiliensis Lymphadenitis: 

Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in
fibrosis (A) and well-formed ... seen within giant cells ... Lymphadenitis #Pathology #LymphNode ... #Clinical #Microscopy
Signet ring cell histiocytes in lymph node sinuses! This can mimic metastatic adenocarcinoma. Histiocytes have ingested
Signet ring cell ... #SignetRing #Cell ... #Histiocytes #LymphNode ... #Pathology #Clinical ... #Microscopy
Hobnail variant of PTC: micropapillary architecture, dense eosinophilic cytoplasm, hobnail cells with apical nuclei, and marked
Hobnail variant ... cytoplasm, hobnail cells ... Carcinoma #Pathology #Clinical ... #Microscopy
Oncocytic Variant of Medullary Carcinoma
Don't assume every oncocytic thyroid tumor is a Hurthle cell neoplasm! Nested
Oncocytic Variant ... tumor is a Hurthle cell ... for oncocytic variant ... Carcinoma #Pathology #Microscopy ... #Clinical
Aldosteronoma — Spironolactone Bodies 

1. Spironolactone is often used to treat hypertension caused by hyperaldosteronism, and
Red blood cells ... endoplasmic reticulum in cells ... Bodies #Pathology #Clinical ... #Gross #Microscopy
A morphologic mosaic of NUT carcinoma: monotonous primitive cells, basophilic to clear cytoplasm, abrupt keratinization, prominent
monotonous primitive cells ... -NUT fusion or variants ... carcinoma #Pathology #Clinical ... #Microscopy #Mosaic